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Archer™ FUSIONPlex™ Acute Lymphoblastic Leukemia panel

Discover ALL insights with a targeted RNA panel

Identify known and novel fusions, splice variants, single nucleotide variants, insertions, deletions, and expression levels with targeted NGS of 81 genes relevant for acute lymphoblastic leukemia research.

Detect more with Archer FUSIONPlex NGS Panels for RNA. 

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Product details

Panel specifications

Specifications
Targeted genes81
Genomic alterationsFusions, splicing, exon-skipping, SNVs, indels, expression levels
Input nucleic acid required*≥10 ng
Recommended number of reads1.5 M
Hands-on time<3.5 hours
Total library prep time1.5 days
Platform compatibilityIllumina® and Ion Torrent™
Reagent formatLyophilized or liquid†
Supported sample typesBlood, bone marrow, fresh frozen, FFPE, BMMC, PBMC

*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50 ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200 ng is recommended.

†Liquid reagents available for Illumina platform only.

Gene targets

ABL1
ABL2
AICDA
BCL11B
BCL2
BCL6
BCR
BLNK
BRAF
CD274
CHD1
CREBBP
CRLF2
CSF1R
CTLA4
DNM2
DNTT
EBF1
EPOR
ETV6
EZH2
FBXW7
FGFR1
FLT3
HOXA10
HOXA9
IDH1
IDH2
IKZF1
IKZF2
IKZF3
IL7R
IRF4
IRF8
JAK1
JAK2
JAK3
KDM6A
KLF2
KMT2A
KRAS
LMO1
LYL1
MLLT4
MPL
MYC
NF1
NOTCH1
NRAS
NT5C2
NTRK3
NUP214
NUP98
P2RY8
PAG1
PAX5
PBX1
PDCD1
PDCD1LG2
PDGFRA
PDGFRB
PICALM
PTK2B
PTPN11
RAG1
RAG2
RUNX1
SEMA6A
SETD2
SH2B3
SOX11
STAT3
STAT5B
STIL
TAL1
TCF3
TLX1
TLX3
TYK2
WT1
ZCCHC7

Interested in adding a few genes to this panel?

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Benefits

  • Detect more—Comprehensive fusion identification is enabled by open-ended targeted amplification, delivering detection of both novel and known fusions, while Archer Analysis’s multifeatured pipeline provides data confidence and clear visualization of breakpoints.
  • Less QNSAnchored Multiplex PCR (AMP™) chemistry is designed for compatibility with a wide range of sample types, including low-input and degraded samples such as FFPE tissue.
  • Achieve efficiency—Streamlined workflows for your lab are enabled by choice of reaction-sized lyophilized reagents or high-throughput liquid reagents, while parallel workflows across all Archer panels provide efficient genomic characterization.
  • Customize content—Use Assay Marketplace to modify any panel to fit your lab’s needs or start from scratch to keep up with the pace of discovery.

Ready to start?

Talk with our technical sales team. Learn how the FUSIONPlex Acute Lymphoblastic Leukemia panel can identify key genomic alterations for your research.

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Frequently asked questions

Related products

References

RUO23-2358_001