Archer™ FUSIONPlex™ Core Solid Tumor panel

Discover key solid tumor insights with a targeted RNA panel first

Identify known and novel fusions, splice variants, single nucleotide variants, insertions, deletions, and relative RNA expression with targeted NGS of 57 core genes relevant for colorectal, breast, melanoma, thyroid, gastric, pancreatic, CNS, NSCLC, and other cancer research.

Detect more with Archer FUSIONPlex NGS panels for RNA.

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Learn how the FUSIONPlex Core Solid Tumor panel can identify key genomic alterations for your research.

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Product details

Panel specifications

Specifications
Targeted genes57
Genomic alterationsFusions, splicing, exon-skipping, SNVs, indels, relative expression
Input nucleic acid required*≥10 ng
Recommended number of reads3 M
Hands-on time<3.5 hours
Total library prep time1.5 days
Platform compatibilityIllumina® and Ion Torrent™
Reagent formatLyophilized or liquid†
Supported sample typesFFPE, fresh frozen, cytology smear, FNA

*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50 ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200 ng is recommended.

†Liquid reagents available for Illumina platform only.

Gene targets

AKT1
ALK
AXL
BRAF
BRD3
BRD4
CTNNB1
CYSLTR2
DDR2
DNAJB1
EGFR
ERBB2
ERBB4
ERG
ESR1
FGFR1
FGFR2
FGFR3
GNA11
GNAQ
GNAS
H3F3A
HIST1H3B
HRAS
IDH1
IDH2
KEAP1
KIT
KRAS
LTK
MAP2K1
MAP3K3
MAP3K8
MET
MYB
MYBL1
NRAS
NRG1
NTRK1
NTRK2
NTRK3
NUTM1
PAX8
PDGFRA
PIK3CA
POLD1
POLE
PPARG
PRKCA
PRKCB
RAF1
RET
ROS1
STK11
TMPRSS2
TP53
TRIM11

Interested in adding a few genes to this panel?

Customize this NGS panel by adding any of our functionally-tested designs or create a new panel that fits your exact requirements with Assay Marketplace.

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Benefits

  • Detect more—Comprehensive fusion detection is enabled by open-ended targeted amplification, delivering identification of both novel and known fusions, while Archer Analysis's multifeatured pipeline provides data confidence and clear visualization of breakpoints.
  • Less QNSAnchored Multiplex PCR (AMP™) chemistry is designed for compatibility with a wide variety of sample types, including low-input and potentially degraded samples such as FFPE tissue.
  • Achieve efficiency—Streamlined workflows for your lab are enabled by choice of reaction-sized lyophilized reagents or high-throughput liquid reagents, while parallel workflows across all Archer panels provide efficient genomic characterization.
  • Customize content—Use Assay Marketplace to modify any panel to fit your lab's needs or start from scratch to keep up with the pace of discovery.

Ready to start?

Talk with our technical sales team. Learn how the FUSIONPlex Core Solid Tumor panel can identify key genomic alterations for your research.

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Frequently asked questions

Related products

References

RUO23-2286_001