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Archer™ FUSIONPlex™ Pan-Heme panel

Discover pan-heme malignancy insights with one targeted panel

Identify known and novel fusions, splice variants, single nucleotide variants, insertions, deletions, and expression levels with targeted NGS of 199 genes relevant for lymphoid and myeloid malignancies research.

Detect more with Archer FUSIONPlex NGS Panels for RNA.

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Learn how the FUSIONPlex Pan-Heme panel can identify key genomic alterations for your research.

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Product details

Panel specifications

Specifications
Targeted genes199
Genomic alterationsFusions, splicing, exon-skipping, SNVs, indels, expression levels
Input nucleic acid required*≥10 ng
Recommended number of reads4.5 M
Hands-on time<3.5 hours
Total library prep time1.5 days
Platform compatibilityIllumina® and Ion Torrent™
Reagent formatLyophilized or liquid†
Supported sample typesBlood, bone marrow, FFPE, fresh frozen, BMMC, PBMC 

*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50 ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200 ng is recommended.

†Liquid reagents available for Illumina platform only.

Gene targets

ABL1
ABL2
AICDA
AKT3
ALK
ASB13
ASXL1
BATF3
BAX
BCL11B
BCL2
BCL2A1
BCL3
BCL6
BCR
BIRC3
BLNK
BMF
BMP7
BRAF
BTK
CALR
CARD11
CBFB
CBL
CCDC50
CCND1
CCND2
CCND3
CD274
CD44
CD79B
CDC25A
CDK6
CDKN2A
CDKN2B
CEBPA
CEBPD
CEBPE
CEBPG
CHD1
CHIC2
CIITA
CREB3L2
CREBBP
CRLF2
CSF1R
CSF3R
CTLA4
CYB5R2
DCK
DEK
DENND3
DLEU1
DNM2
DNMT3A
DNMT3B
DNTT
DUSP22
E2F2
EBF1
EIF4A1
ENTPD1
EPOR
ERG
ETV6
EXOC2
EZH2
FAM216A
FBXW7
FGFR1
FGFR2
FGFR3
FLT3
FOXP1
FUT8
GATA1
GATA2
GLIS2
GNAS
HOXA10
HOXA9
ID4
IDH1
IDH2
IKZF1
IKZF2
IKZF3
IL16
IL7R
IRF4
IRF8
ITPKB
JAK1
JAK2
JAK3
KAT6A
KDM6A
KIAA0101
KIT
KLF2
KMT2A
KRAS
LIMD1
LMO1
LMO2
LRMP
LYL1
LZTS1
MAL
MALT1
MAML3
MECOM
MKL1
MLF1
MLLT10
MLLT4
MME
MPL
MUC1
MYBL1
MYC
MYD88
MYH11
NEK6
NF1
NFKB1
NFKB2
NME1
NOTCH1
NOTCH2
NPM1
NRAS
NT5C2
NTRK3
NUP214
NUP98
P2RY8
PAG1
PAICS
PAX5
PBX1
PDCD1
PDCD1LG2
PDGFRA
PDGFRB
PHF6
PICALM
PIM1
PIM2
PLCG1
PLCG2
PML
PPAT
PRDM16
PRKAR2B
PTK2B
PTPN1
PTPN11
PYCR1
RAB29
RAG1
RAG2
RANBP1
RARA
RBM15
RHOA
ROS1
RUNX1
RUNX1T1
S1PR2
SEMA6A
SERPINA9
SETBP1
SETD2
SF3B1
SH2B3
SH3BP5
SLC29A1
SOX11
SRSF2
STAT3
STAT5B
STAT6
STIL
STRBP
TAL1
TCF3
TFG
TLX1
TLX3
TNFRSF13B
TNFSF4
TP63
TYK2
U2AF1
WT1
XPO1
ZCCHC7

Interested in adding a few genes to this panel?

Customize this NGS panel by adding any of our functionally-tested designs or create a new panel that fits your exact requirements with Assay Marketplace.

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Benefits

  • Detect more—Comprehensive fusion identification is enabled by open-ended targeted amplification, delivering detection of both novel and known fusions, while Archer Analysis’s multifeatured pipeline provides data confidence and clear visualization of breakpoints.
  • Less QNSAnchored Multiplex PCR (AMP™) chemistry is designed for compatibility with a wide range of sample types, including low-input and degraded samples such as FFPE tissue.
  • Achieve efficiency—Streamlined workflows for your lab are enabled by choice of reaction-sized lyophilized reagents or high-throughput liquid reagents, while parallel workflows across all Archer panels provide efficient genomic characterization.
  • Customize content—Use Assay Marketplace to modify any panel to fit your lab’s needs or start from scratch to keep up with the pace of discovery.

Ready to start?

Talk with our technical sales team. Learn how the FUSIONPlex Pan-Heme panel can identify key genomic alterations for your research.

Request a consultation

Frequently asked questions

Related products

References

RUO23-2368_001